THE "CAPS" REGISTRY-5

Table 5. Thrombotic clinical manifestations of patients at the time of catastrophic APS.

PATIENT No.	ADRENAL			HEMATOLOGICAL	OTHER
	CLINICAL	IMAGING	BIOPSY		ORGAN	CLINICAL	IMAGING	BIOPSY
1					Retina	Blurred vision Decresed visual acuity	Infarct
2
3					Retina		Thrombi Infarct
4					Pancreas			Microthrombi
5 (1^st)
5 (2^nd)			Bilateral hemorrhage
6			Sinusoidal fibrin Haemorrhage	TMHA	Myometrium Pituitary			Microthrombi Focal necrosis
7
8					Nerve	Mononeuritis	denervacion
9
10	Addison	infarct
11					Ears	Necrosis
12				DIC	Nasal Bone marrow	Ulcers Avascular necrosis		Microthrombi
13	Addison	Enlarged	Hemorrhagic infarct microthrombi	DIC	Testicles	Enlarged		Multiple thrombi
14				DIC
15					Pancreas	Pancreatitis
16
17	Yes				Bone Meninges
18
19				DIC	Aorta			Thrombi
20			Veins thrombi
21 (1^st)				TMHA
(2sn)	Addison	Infarct		TMHA	Nerve Pancreas	Mononeuritis Pancreatitis
22			Infarct	DIC
23				DIC	Pancreas			Microthrombi
24					Pancreas	Pain		Microthrombi
25					Gallbladder
26					Retina	Blurred vision	Central retinal vein thrombi
27
28
29	Yes				Esophagus Testicles Traquea
30
31				TMHA
32
33				DIC	Pancreas	Pancreatitis
34				DIC	Retina	Decresed vision	Arteriolar oclussion
35				DIC	Nose Ocular	ulcers	Vascular oclussion
36			Microthrombi		Thyroid Muscle Nerve			Microthrombi
37
38
39				DIC
40				DIC
41
42
43
44
45					Prostate
46
47			microthrombi
48
49					Retina		Central vein thrombi
50					Bronquial			Artery thrombi
51				DIC
52				DIC
53
54					Uterus Ovary Bladder Pancreas			Microthrombi
55
56
57
58					Knees		Vascular necrosis
59				DIC	Bone marrow			Ischemic necrosis
60					Bone marrow		infarcts
61					Bone marrow Ocular			Ischemia
62					Nerves	Paralysis
63
64				DIC
65
66					Gallbladder	Pain	Infarcts	Microthrombi
67
68				TMHA	Pancreas			Microthrombi
69				DIC
70(1st)
(2nd)
(3rd)
71				DIC	Abdominal aorta		Thrombi
72
73
74					Nerve	Peripheral neuropathy
75
76						Transverse myelitis
77						Transverse myelitis
78						Transverse myelitis
79					Nerve	Peripheral neuropathy
80					Muscle
81					Nerve	Peripheral neuropathy
82
83(1st)	Addison	Enlarge		TMHA
83(2nd)	Addison			TMHA
84	addison
85			Microthrombi		Thyroid Pancreas Muscle Nerve			Microthrombi
86
87				DIC		Pancreas	Pancreatitis
88				DIC	Retina	Blurred vision	Vein oclussion
89					Retina	Decresed visual acuity	microthrombi
90
91			Microthrombi		Uterus			Microthrombi
92			Central vein thrombi		Gallbladder Vertebral			Microinfarcts
93
94					Pleura			Microthrombi
95
96					Ovaries			Microthrombi
97
98
99
100					Bone marrow
101
102				DIC
103				DIC
104
105				DIC
106
107			Enlarged Fibrosis		Pancreas Cerebellum Parathyroids			Microthrombi
108
109				DIC	Nerve	Mononeuritis
110				TMHA	Cranial nerve 6^TH	Paralysis
111
112					Pancreas	Pancreatitis
113		Bilateral hemorrhage
114
115
116					Gallbladder Pancreas	Jaundice Pancreatitis		Microinfarcts -
117	Hypertension	Enlatged	Hemorrhage Necrosis microthrombi
118
119				DIC
120					Retina	Artery thrombi
121
122
123				DIC
124					Nerve	Paresthesias
125
126
127				DIC	Pancreas
128
129
130
131			Multiple infarcts		Uterus			Microthrombi
132		Infarct
133				TMHA
134				NR
135
136				NR