Euro-Phospholipid on Line

Official Web-site of the "European Forum on Antiphospholipid Antibodies"

MULTICENTRE STUDIES

EURO-PHOSPHOLIPID PROJECT


PROSPECTIVE STUDY OF THE CLINICAL AND SEROLOGICAL CHARACTERISTICS AND LONG-TERM EVOLUTION OF THE ANTIPHOSPHOLIPID SYNDROME (APS) IN THE EUROPEAN POPULATION ("EURO-PHOSPHOLIPID" PROJECT)

COORDINATORS

Ricard Cervera, Josep Font Marie-Claire Boffa, Jean Charles Piette, Munther A. Khamashta and Graham R.V. Hughes on behalf of the European Forum on Antiphospholipid Antibodies.

AIM

To evaluate prospectively the clinical and serological manifestations and the long-term evolution of the APS by means of a 10-year-follow-up study of 1000 patients attending 20 European university centres with experience in the management of this disorder.

OBJECTIVES

1. To determine the incidence and characteristics of the different APS clinical manifestations at the onset of the disease and during the follow-up.

2. To analyse the biological and immunological features of these patients and the relationship with their clinical manifestations in order to clearly define different subsets of the disease.

3. To determine the natural history, severity and response to treatment of these APS subsets.

4. To evaluate the morbidity of the different APS subsets (including the complications induced by the different treatment regimens of this condition).

5. To establish the mortality rate and the main causes of death in the European APS population.

For ongoing results, please click ”EURO-PHOSPHOLIPID PROJECT” AT A GLANCE

For additional information and applications, please e-mail: rcervera@clinic.ub.es


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Last updated: 2 February 2005